• Damages the player for half a heart. If the player has armor, the damage will remove the armor.
• Increases Coolness by 1 per use, decreasing the cooldown of active items and increasing the chance of items dropping upon clearing a room. The coolness bonus will remain for the entire run, even if the Cigarettes are removed from the player's inventory.
• Discarded cigarettes will light oil puddles and Phaser Spider webs.

• Iroquois - If the player has [MAC10] , the [MAC10] 's reload time is decreased by 33%, magazine size is increased by 50%, and knockback is increased by 50%.
• What A Thrill - If the player has [Patriot] , [Patriot] has a chance to transmogrify enemies into snakes.
• I need scissors! 61! - If the player also has [Trank Gun] . [Trank Gun] changes appearance, its rate of fire is decreased, damage and reload time are increased, and its bullets will inflict slow and stun .
• If the player has Armor , Cigarettes can be used to offensively detonate the blank effect. Consider offensive combinations like [Gunknight Armor] pieces or [Nanomachines] .
• Dying to Cigarettes will produce "Smoking" as a cause of death.
• If the player has [Crisis Stone] , they can get infinite coolness by using Cigarettes during [Crisis Stone] 's invulnerability periods.
• If the player has invulnerability items such as [Stuffed Star] or [Ring of Ethereal Form] , activating it will disable the use of Cigarettes for the duration.
• If the player has [GuNNER] and [Holey Grail] , they can get infinite coolness by using Cigarettes while holding [GuNNER] and picking up the skull after each use. Incidentally, this also grants the player infinite ammo for all guns.
• If the player has [Gun Soul] , they can get infinite coolness by using Cigarettes until dying, activating [Gun Soul] and using its revive effect. It should be noted that the player is left at one heart after the fact, making this strategy risky.
• If the player has [Full Metal Jacket] and at least one blank or a charged [Elder Blank] , using Cigarettes will activate a blank and prevent damage from being dealt.
• Be careful not to use the Cigarettes during boss fights, as using it counts as damage taken, causing you to lose the [Master Round] in the process if you have not taken any damage prior.

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